2013-2014 Bioprocess engineer

DSM (Patheon) Biologics, Groningen, the Netherlands

Scientific coordination of the manufacture (USP) and purification (DSP) of protein-based pharmaceuticals performed under cGMP conditions. This included (i) fermentation processes, ranging in scale from 50-1000 L and (ii) purification of proteins, using different chromatographic techniques.

 

 Achievements:

• Ensured robust and reproducible upstream process operation.

• Initiated and coordinated improvement processes together with QA department, improving

   process operability.

• Investigated deviations and performed root cause analysis, ameliorating process robustness.

• Authored cGMP documentation, enabling efficient process operation.

• Wrote techical and quality documents,

• Monitored compliance of manufacturing steps with quality standards together with QA

  department, ensuring process quality.

• Supervised collection of QC samples of process intermediates.

• Implemented and improved novel or existing manufacturing processes.

• Functioned as primary client contact for production processes.